Glycogen Metabolism in the Normal Red Blood Cell
نویسندگان
چکیده
منابع مشابه
Glycogen metabolism in the normal red blood cell.
Evidence for active glycogen metabolism in normal mature red blood cells (RBC) is presented. Initial rates of ‘4C-U-glucose incorporation into erythrocyte glycogen were found to be independent of substrate concentration over a range of 3.3-16.6 mM. Incorporation of label into glycogen was initially linear but reached a plateau after a variable period of time that was Inversely related to RBC co...
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The RBC histogram is an integral part of automated hematology analysis and is now routinely available on all automated cell counters. This histogram and other associated complete blood count (CBC) parameters have been found abnormal in various hematological conditions and may provide major clues in the diagnosis and management of significant red cell disorders. In addition, it is frequently use...
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Glycogen phosphorylase has been assayed in normal leukocytes and in those ob tained from patients with chronic granulocytic and chronic lymphocytic leukemia. Assay was performed in the direction of both glycogen degradation and glycogen syn thesis with and without adenylic acid. The results indicate that (a) a major portion of phosphorylase activity exists in the active or a form as evidenced b...
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Red blood cell metabolism was studied in vitro using whole blood obtained by catheter from resting rainbow trout (Oncorhynchus mykiss). Preparations were viable as shown by stable NTP, metabolite and catecholamine levels and acid-base status, all of which remained at in vivo levels over the 2 h incubation period. Enzymes diagnostic of glycolysis, the tricarboxylic acid (TCA) cycle and phosphage...
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We studied the anti-IgG-induced agglutination of both normal and abnormal red blood cells (RBC) using a sensitive, automated antiglobulin test. Normal RBC agglutinated strongly with anti-IgG antibody, indicating that IgG was present on the erythrocyte membrane. Young RBC, recovered by centrifugation from a normal RBC population, agglutinated with anti-IgG less than the old cells, suggesting tha...
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ژورنال
عنوان ژورنال: Blood
سال: 1972
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v40.6.836.836